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| | 9460万，赌AlphaFold没走的那条路 | | | 新智元 ｜ 2026-09-28 | | | |
| 声明： 本消息或因风格和篇幅原因进行过编辑，但未经核实，也不代表我们的立场、观点或建议。如有侵权，联系秒删。[ 使用条款 ] |
scroll 0 1 AlphaFold几乎把自然界2亿多种蛋白质结构预测了一遍。
David Baker想走另一条路：不预测自然造了什么，而是造出自然从没造过的东西。
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今年8月的一个早上，研究助理Jack Boylan调出前一晚的实验结果。
实验室的DNA测序仪旁，试管里泡着一大批人工设计的DNA序列，都是自然界从未进化出来的。哪条能用、哪条是废品，全靠这台机器一次读完、一次报出。
不久前的一次实验，他们把600万条这样的设计序列一起丢进同一支试管，同时测。换成传统做法，光是测这一批就得花上好几年。
Boylan所在的这家机构叫AI BioDesign，9月3日刚在西雅图对外亮相，距离艾伦研究所总部不过几分钟路程。
它背后是保罗·艾伦遗产体系砸下的9460万美元，领头人正是2024年诺贝尔化学奖得主Baker和基因组学家Jay Shendure。
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左：David Baker，2024年诺贝尔化学奖得主。右：Jay Shendure，基因组学家。两人共同领衔AI BioDesign。
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